Drug discovery using next-generation antibodies and aptamers against GPCR.
- At least a hundred of membrane proteins will be potential candidates of antigens for antibody drug.
- will extend the target domain of antigens for antibody drug.
Collaborative developments and contracted researches related with some next-generation antibodies(EME Cyclic peptide library,Camelid single heavy-chain antibody) and aptamers using cDNA display that is an in vitro peptide and protein selection has been developed by Saitama University researchers.
- Drug discovery and development of next generation antibodies including peptide aptamers against GPCR and other drug targets (collaborative research and alliance with pharmaceutical companies)
- Contracted Research and Development (Next generation antibodies, peptide aptamers)
- Sale of research regents for cDNA display (academic researchers only)
１）cDNA display screening starter kit（Price, 400,000 yen；excluding consumption tax）
２）cnvK linker （Price, 200,000 yen；excluding consumption tax）
The research of evolutionary molecular engineering has started at Saitama University (Japan).
In vitro virus (mRNA display) method (one of virus-like genotype-phenotype linking strategies) was developed by Dr. Nemoto, Prof. Husimi, Dr. Yanagawa (Mitsubishi Kagaku Institute of Life Sciences & Saitama University).
cDNA display method (improved version of mRNA display) was developed by Dr. Nemoto and his colleagues at Saitama-Bio project (JST)/ The National Institute of Advanced Industrial Science and Technology (AIST)/ Saitama University.
High-speed preparation method of cDNA display was developed by collaborating with Prof. Fujimoto (Japan Advanced Institute of Science and Technology; JAIST).
Filing of patent application for high-throughput system of cDNA display screening (exclusive license for use of the patent from Saitama University)
EME was established at Saitama University.
EME started business at Room 201 of Open Innovation Research Center in the campus of Saitama University.
- Corporate name
Epsilon Molecular Engineering, Inc.
- Head office location
August 19, 2016
- Business description
■ Research and development of biotechnology
■ Contracted research of biotechnology
■ Consulting of biotechnology
■ Information management service of Bioinformatics
Scientific Advisory Board
(Evolutionary Molecular Engineering)
(Japan Advanced Institute of Science and Technology; JAIST, Nucleic Acids Chemistry)
(Saitama University, Optical Imaging)
(Saitama University, Cell-free translation system)
(Ryukyu University, Construction of Biological library)
(National Institute of Advanced Industrial Science and Technology; AIST, Membrane protein)